Increased building block access through collaboration-Reference-Cited by-同舟云学术

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Increased building block access through collaboration

Published:2018-08 Issue:8 Volume:23 Page:1458-1462
ISSN:1359-6446
Container-title:Drug Discovery Today
language:en
Short-container-title:Drug Discovery Today

Author:

Helal Christopher J.,Bartolozzi Alessandra,Goble Steven D.,Mani Neelakanda S.,Guzman-Perez Angel,Ohri Ajay K.,Shi Zhi-Cai,Subramanyam Chakrapani

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference13 articles.

1. Identification of a brain penetrant PDE9A inhibitor utilizing prospective design and chemical enablement as a rapid lead optimization strategy;Verhoest;J. Med. Chem.,2009

2. Design and Discovery of 6-[(3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (PF-04447943), a Selective Brain Penetrant PDE9A Inhibitor for the Treatment of Cognitive Disorders

3. Designing novel building blocks is an overlooked strategy to improve compound quality;Goldberg;Drug Discov. Today,2015

4. The role of fluorine in medicinal chemistry;Shah;J. Enzyme Inhib. Med. Chem.,2007

5. Applications of fluorine in medicinal chemistry;Gillis;J. Med. Chem.,2015

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2. Cheminformatics Approaches Aiding the Design and Selection of DNA-Encoded Libraries;Topics in Medicinal Chemistry;2022

3. Emerging Building Blocks for Medicinal Chemistry: Recent Synthetic Advances;European Journal of Organic Chemistry;2021-11-18

4. Synthesis and functionalisation of a bifunctional normorphan 3D building block for medicinal chemistry;Tetrahedron;2021-03

5. Positional Analogue Scanning: An Effective Strategy for Multiparameter Optimization in Drug Design;Journal of Medicinal Chemistry;2020-04-24

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