Improved Validated Assay for the Determination of Proguanil and Its Metabolites in Plasma, Whole Blood, and Urine Using Solid-Phase Extraction and High-Performance Liquid Chromatography-Reference-Cited by-同舟云学术

Improved Validated Assay for the Determination of Proguanil and Its Metabolites in Plasma, Whole Blood, and Urine Using Solid-Phase Extraction and High-Performance Liquid Chromatography

Published:1998-06 Issue:3 Volume:20 Page:325-330
ISSN:0163-4356
Container-title:Therapeutic Drug Monitoring
language:en
Short-container-title:Therapeutic Drug Monitoring

Author:

Bergqvist Yngve,Funding Lars,Krysèn Birgitta,Leek Tomas,Yvell Karin

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Pharmacology (medical),Pharmacology

Reference18 articles.

1. In vitro metabolism of the biguanide antimalarials in human liver microsomes: evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme.

2. The activation of the biguanide antimalarial proguanil co-segregates with the mephenytoin oxidation polymorphism-a panel study.

3. High-performance liquid chromatographic method for the determination of proguanil and cycloguanil in biological fluids

4. Simultaneous measurement of proguanil and cycloguanil in human plasma by high-performance liquid chromatography

5. A Simple HPLC Assay for Proguanil and Its Active Metabolite Cycloguanil: Application to Oxidation Phenotyping

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2. Formation of the diuretic chlorazanil from the antimalarial drug proguanil—Implications for sports drug testing;Journal of Pharmaceutical and Biomedical Analysis;2015-11

3. Analyses of Biguanides and Related Compounds in Biological and Environmental Samples by HPLC;Journal of Liquid Chromatography & Related Technologies;2014-10-31

4. ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR SIMULTANEOUS DETERMINATION OF ATOVAQUONE AND PROGUANIL IN RABBIT PLASMA AND ITS APPLICATION TO A PHARMACOKINETIC STUDY;Journal of Liquid Chromatography & Related Technologies;2014-04-03

5. Solid-Phase Extraction and Clean-Up Procedures in Pharmaceutical Analysis;Encyclopedia of Analytical Chemistry;2012-12-17