mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent-Reference-Cited by-同舟云学术

mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent

Published:2021-11-17 Issue:620 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Sajid Andaleeb¹^ORCID,Matias Jaqueline¹^ORCID,Arora Gunjan¹^ORCID,Kurokawa Cheyne¹,DePonte Kathleen¹,Tang Xiaotian¹^ORCID,Lynn Geoffrey¹^ORCID,Wu Ming-Jie¹,Pal Utpal²³^ORCID,Strank Norma Olivares¹,Pardi Norbert⁴^ORCID,Narasimhan Sukanya¹^ORCID,Weissman Drew⁴^ORCID,Fikrig Erol¹^ORCID

Affiliation:

1. Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

2. Department of Veterinary Medicine, University of Maryland, College Park, MD 20472, USA.

3. Virginia-Maryland Regional College of Veterinary Medicine, College Park, MD 20472, USA.

4. Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Abstract

An Ixodes scapularis saliva mRNA vaccine induces tick resistance and prevents Borrelia burgdorferi infection in guinea pigs.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference90 articles.

1. The Blacklegged Tick, Ixodes scapularis : An Increasing Public Health Concern

2. Human pathogens associated with the blacklegged tick Ixodes scapularis: a systematic review

3. Incidence of Clinician-Diagnosed Lyme Disease, United States, 2005–2010

4. CDC Lyme disease data tables: Most recent year (2018); https://www.cdc.gov/lyme/datasurveillance/tables-recent.html.

5. Vital Signs: Trends in Reported Vectorborne Disease Cases — United States and Territories, 2004–2016

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