Extremely drug-resistant NDM-9-producing ST147 Klebsiella pneumoniae causing infections in Italy, May 2020-Reference-Cited by-同舟云学术

Extremely drug-resistant NDM-9-producing ST147 Klebsiella pneumoniae causing infections in Italy, May 2020

Published:2020-12-03 Issue:48 Volume:25 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Falcone Marco¹²,Giordano Cesira³¹,Barnini Simona³,Tiseo Giusy²,Leonildi Alessandro³,Malacarne Paolo⁴,Menichetti Francesco²,Carattoli Alessandra⁵^ORCID

Affiliation:

1. The authors contributed equally this article

2. Infectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

3. Microbiology Unit, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy

4. Department of Anaesthesia and Critical Care Medicine, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy

5. Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy

Abstract

A large outbreak of New Delhi metallo-beta-lactamase (NDM)-1-producing Klebsiella pneumoniae sequence type (ST) 147 occurred in Tuscany, Italy in 2018–2019. In 2020, ST147 NDM-9-producing K. pneumoniae were detected at the University Hospital of Pisa, Tuscany, in two critically ill patients; one developed bacteraemia. Genomic and phylogenetic analyses suggest relatedness of 2018–2019 and 2020 strains, with a change from NDM-1 to NDM-9 in the latter and evolution by colistin, tigecycline and fosfomycin resistance acquisition.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference14 articles.

1. Prolonged outbreak of New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019.;Tavoschi;Euro Surveill,2020

2. Clinical features and outcomes of bloodstream infections caused by New Delhi metallo-β-lactamase-producing Enterobacterales during a regional outbreak.;Falcone;Open Forum Infect Dis,2020

3. Monitoring ceftazidime-avibactam and aztreonam concentrations in the treatment of a bloodstream infection caused by a multidrug-resistant Enterobacter sp. carrying both Klebsiella pneumoniae carbapenemase-4 and New Delhi metallo-β-lactamase-1.;Yasmin;Clin Infect Dis,2020

4. In silico detection and typing of plasmids using PlasmidFinder and Plasmid Multilocus Sequence Typing.;Carattoli;Antimicrob Agents Chemother,2014

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