Prolonged outbreak of New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019-Reference-Cited by-同舟云学术

Prolonged outbreak of New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019

Published:2020-02-13 Issue:6 Volume:25 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Tavoschi Lara¹,Forni Silvia²,Porretta Andrea³¹,Righi Lorenzo⁴,Pieralli Filippo⁵,Menichetti Francesco³,Falcone Marco³,Gemignani Giulia³,Sani Spartaco⁶,Vivani Paola⁷,Bellandi Tommaso⁸,Tacconi Danilo⁹,Turini Lucia¹⁰,Toccafondi Giulio⁴,Privitera Gaetano³¹,Lopalco Pierluigi³¹,Baggiani Angelo³¹,Gemmi Fabrizio²,Luchini Grazia³,Petrillo Maurizio¹¹,Roti Lorenzo¹⁰,Pezzotti Patrizio¹²,Pantosti Annalisa¹²,Iannazzo Stefania¹³,Mechi Maria Teresa⁴,Rossolini Gian Maria¹⁴⁵,

Affiliation:

1. Department of Translational Research and New technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

2. Regional Health Agency of Tuscany, Florence, Italy

3. University Hospital of Pisa, Pisa, Italy

4. Quality of care and Clinical networks, Tuscany Region, Florence, Italy

5. Florence Careggi University Hospital, Florence, Italy

6. Livorno Hospital, Toscana North-West Health Authority, Livorno, Italy

7. Massa Carrara Hospital, Toscana North-West Health Authority, Massa Carrara, Italy

8. Toscana North-West Health Authority, Lucca, Italy

9. Arezzo Hospital, Toscana South-East Health Authority, Arezzo, Italy

10. Toscana North-West Health Authority, Pisa, Italy

11. Fondazione Toscana Gabriele Monasterio, Pisa, Italy

12. Istituto Superiore di Sanità, Rome, Italy

13. Ministry of Health, Rome, Italy

14. Department of Experimental Medicine, University of Florence, Florence, Italy

Abstract

In Tuscany, Italy, New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE) have increased since November 2018. Between November 2018 and October 2019, 1,645 samples were NDM-CRE-positive: 1,270 (77.2%) cases of intestinal carriage, 129 (7.8%) bloodstream infections and 246 (14.9%) infections/colonisations at other sites. Klebsiella pneumoniae were prevalent (1,495; 90.9%), with ST147/NDM-1 the dominant clone. Delayed outbreak identification and response resulted in sustained NDM-CRE transmission in the North-West area of Tuscany, but successfully contained spread within the region.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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3. Carbapenemase-producing Enterobacteriaceae in Europe: assessment by national experts from 38 countries, May 2015.;Albiger;Euro Surveill,2015

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