Synthesis and Evaluation of 1-Arylsulfonyl-3-piperazinone Derivatives as Factor Xa Inhibitors VI. A Series of New Derivatives Containing N,S- and N,SO2-Spiro Acetal Scaffolds-Reference-Cited by-同舟云学术

Synthesis and Evaluation of 1-Arylsulfonyl-3-piperazinone Derivatives as Factor Xa Inhibitors VI. A Series of New Derivatives Containing N,S- and N,SO2-Spiro Acetal Scaffolds

Published:2007 Issue:2 Volume:55 Page:317-323
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

Saitoh Fumihiko¹,Nishida Hidemitsu¹,Mukaihira Takafumi¹,Kosuga Naoto¹,Ohkouchi Munetaka¹,Matsusue Tomokazu¹,Shiromizu Ikuya¹,Hosaka Yoshitaka¹,Matsumoto Miwa¹,Yamamoto Ichiro¹

Affiliation:

1. Pharmaceutical Research Center, Mochida Pharmaceutical Co., Ltd.

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

http://www.jstage.jst.go.jp/article/cpb/55/2/55_2_317/_pdf

Reference43 articles.

1. Synthesis and Evaluation of 1-Arylsulfonyl-3-piperazinone Derivatives as Factor Xa Inhibitor.

2. Synthesis and Evaluation of 1-Arylsulfonyl-3-piperazinone Derivatives as a Factor Xa Inhibitor. II. Substituent Effect on Biological Activities.

3. Synthesis and Evaluation of 1-Arylsulfonyl-3-piperazinone Derivatives as Factor Xa Inhibitors III. Effect of Ring Opening of Piperazinone Moiety on Inhibition