Synthesis and Evaluation of 1-Arylsulfonyl-3-piperazinone Derivatives as Factor Xa Inhibitor.
Author:
Affiliation:
1. Chemistry Laboratory, Research Center, Mochida Pharmaceutical Co., Ltd.
Publisher
Pharmaceutical Society of Japan
Subject
Drug Discovery,General Chemistry,General Medicine
Link
http://www.jstage.jst.go.jp/article/cpb/49/10/49_10_1237/_pdf
Reference28 articles.
1. Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profile
2. The coagulation cascade: initiation, maintenance, and regulation
3. Factor Xa inhibitors by classical and combinatorial chemistry
4. Optimization of conditions for the catalytic effect of the factor IXa - Factor VIII complex
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