Comparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cells-Reference-Cited by-同舟云学术

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Comparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cells

Published:2002-01 Issue:11 Volume:32 Page:937-947
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Andrews J.,Abd-Ellah M. F.,Randolph N. L.,Kenworthy K. E.,Carlile D. J.,Friedberg T.,Houston J. B.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/00498250210163289

Reference29 articles.

1. Pharmacology of Dormicum (midazolam) and Anexate (flumazenil)

2. Diazepam metabolism by human liver microsomes is mediated by both S- mephenytoin hydroxylase and CYP3A isoforms.

3. Simultaneous Determination of Dextromethorphan and Three Metabolites in Plasma and Urine Using High-Performance Liquid Chromatography with Application to Their Disposition in Man

4. Xenobiotic-metabolizing human cells as tools for pharmacological and toxicological research

5. Use of cDNA-Expressed Human Cytochrome P450 Enzymes to Study Potential Drug-Drug Interactions

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2. Metabolism-Based Drug-Drug Interactions in Critically Ill Patients: Clinical Relevance and Predictability ofIn VitroSystems;Encyclopedia of Drug Metabolism and Interactions;2016-06-15

3. Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity;Drug Metabolism and Disposition;2013-12-11

4. A Semi-Mechanistic Metabolism Model of CYP3A Substrates in Pregnancy: Predicting Changes in Midazolam and Nifedipine Pharmacokinetics;CPT: Pharmacometrics & Systems Pharmacology;2012-09

5. Mini-series: I. Basic science. Uncertainty and inaccuracy of predicting CYP-mediated in vivo drug interactions in the ICU from in vitro models: focus on CYP3A4;Intensive Care Medicine;2009-01-09

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