Diazepam metabolism by human liver microsomes is mediated by both S- mephenytoin hydroxylase and CYP3A isoforms.
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.1994.tb04336.x/fullpdf
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3. Delayed clearance of diazepam due to cimetidine;Klotz;New Engl J Med,1980
4. Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquine, hydroxylation phenotype;Bertilsson;Clin Pharmac Ther,1989
5. Effect of omeprazole treatment on diazepam plasma levels in slow versus normal rapid metabolizers of omeprazole;Andersson;Clin Pharmac Ther,1990
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