Negative allosteric modulators of group II metabotropic glutamate receptors: A patent review (2015 – present)-Reference-Cited by-同舟云学术

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Negative allosteric modulators of group II metabotropic glutamate receptors: A patent review (2015 – present)

Published:2021-03-31 Issue:8 Volume:31 Page:687-708
ISSN:1354-3776
Container-title:Expert Opinion on Therapeutic Patents
language:en
Short-container-title:Expert Opinion on Therapeutic Patents

Author:

Qunies Alshaima’a M.¹²,Emmitte Kyle A.¹

Affiliation:

1. Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, USA

2. Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX, USA

Funder

The University of North Texas Health Science Center

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/13543776.2021.1903431

Reference109 articles.

1. Group II Metabotropic Glutamate Receptors as Targets for Novel Antipsychotic Drugs

2. Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors

3. Design of 4-Oxo-1-aryl-1,4-dihydroquinoline-3-carboxamides as Selective Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 2

4. Progress toward advanced understanding of metabotropic glutamate receptors: structure, signaling and therapeutic indications

5. Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

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1. Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator;ACS Medicinal Chemistry Letters;2023-07-12

2. Discovery of [¹¹C]MK-8056: A Selective PET Imaging Agent for the Study of mGluR₂ Negative Allosteric Modulators;ACS Medicinal Chemistry Letters;2023-06-13

3. Pharmacological targeting of cognitive impairment in depression: recent developments and challenges in human clinical research;Translational Psychiatry;2022-11-17

4. Targeting mGluR2/3 for treatment of neurodegenerative and neuropsychiatric diseases;Pharmacology & Therapeutics;2022-11

5. Advances in translating mGlu2 and mGlu3 receptor selective allosteric modulators as breakthrough treatments for affective disorders and alcohol use disorder;Pharmacology Biochemistry and Behavior;2022-09

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