Design of 4-Oxo-1-aryl-1,4-dihydroquinoline-3-carboxamides as Selective Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 2-Reference-Cited by-同舟云学术

Design of 4-Oxo-1-aryl-1,4-dihydroquinoline-3-carboxamides as Selective Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 2

Published:2015-11-11 Issue:22 Volume:58 Page:9027-9040
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Felts Andrew S.¹,Rodriguez Alice L.¹,Smith Katrina A.¹,Engers Julie L.¹,Morrison Ryan D.¹,Byers Frank W.¹,Blobaum Anna L.¹,Locuson Charles W.¹,Chang Sichen¹,Venable Daryl F.¹,Niswender Colleen M.¹,Daniels J. Scott¹,Conn P. Jeffrey¹,Lindsley Craig W.¹²,Emmitte Kyle A.¹²

Affiliation:

1. Vanderbilt Center for Neuroscience Drug Discovery, Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States

2. Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37232, United States

Funder

National Institute of Mental Health

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01371

Reference63 articles.

1. Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

2. Pharmacological agents acting at subtypes of metabotropic glutamate receptors