Synthesis and Characterization of 5-(2-Fluoro-4-[11C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide as a PET Imaging Ligand for Metabotropic Glutamate Receptor 2-Reference-Cited by-同舟云学术

Synthesis and Characterization of 5-(2-Fluoro-4-[¹¹C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide as a PET Imaging Ligand for Metabotropic Glutamate Receptor 2

Published:2022-01-28 Issue:3 Volume:65 Page:2593-2609
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yuan Gengyang¹^ORCID,Dhaynaut Maeva¹,Lan Yu²,Guehl Nicolas J.¹^ORCID,Huynh Dalena¹,Iyengar Suhasini M.³^ORCID,Afshar Sepideh¹,Jain Manish Kumar⁴^ORCID,Pickett Julie E.⁴^ORCID,Kang Hye Jin⁴,Wang Hao²,Moon Sung-Hyun¹,Ondrechen Mary Jo³^ORCID,Wang Changning²^ORCID,Shoup Timothy M.¹,El Fakhri Georges¹,Normandin Marc D.¹,Brownell Anna-Liisa¹^ORCID

Affiliation:

1. Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States

2. Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, United States

3. Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States

4. Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, United States

Funder

National Institute of Neurological Disorders and Stroke

National Center for Research Resources

NIH Office of the Director

National Institute of Biomedical Imaging and Bioengineering

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link