Radiosynthesis and Evaluation of 11C-Labeled Isoindolone-Based Positive Allosteric Modulators for Positron Emission Tomography Imaging of Metabotropic Glutamate Receptor 2-Reference-Cited by-同舟云学术

Radiosynthesis and Evaluation of 11C-Labeled Isoindolone-Based Positive Allosteric Modulators for Positron Emission Tomography Imaging of Metabotropic Glutamate Receptor 2

Published:2024-07-10 Issue:8 Volume:7 Page:2414-2423
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Li Yinlong¹,Dahl Kenneth²³,Johnström Peter²³,Varnäs Katarina³^ORCID,Farde Lars³,Halldin Christer³,Medd Amy⁴,Maier Donna⁴,Powell Mark E.⁴,Chen Jiahui¹^ORCID,Van Richard⁵,Patel Jimmy¹,Chaudhary Ahmad¹,Gao Yabiao¹,Song Zhendong¹,Haider Ahmed¹,Shao Yihan⁵^ORCID,Elmore Charles S.⁴⁶,Liang Steven¹^ORCID,Schou Magnus²³^ORCID

Affiliation:

1. Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States

2. PET Science Centre, Precision Medicine and Biosamples, Oncology R&D, AstraZeneca, Karolinska Institutet, Stockholm S-17176, Sweden

3. Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm S-17176, Sweden

4. Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Wilmington, Delaware 19803, United States

5. Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019-5251, United States

6. Early Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca Pharmaceuticals, Gothenburg 43183, Sweden

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.4c00261

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