Prediction of human pharmacokinetics of typical compounds by a physiologically based method using chimeric mice with humanized liver
Author:
Affiliation:
1. Drug Metabolism and Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc, Osaka, Japan;
2. Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Tokyo, Japan
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2018.1460516
Reference38 articles.
1. 5 Human Albumin
2. Physiological Parameter Values for Physiologically Based Pharmacokinetic Models
3. A Perspective on the Prediction of Drug Pharmacokinetics and Disposition in Drug Research and Development
4. Drug Metabolism and Toxicity in Chimeric Mice with Humanized Liver
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