Drug Metabolism and Toxicity in Chimeric Mice with Humanized Liver
Author:
Affiliation:
1. Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University
2. Business Development Division, Contract Research Company, Shin Nippon Biomedical Laboratories, Ltd.
Publisher
Pharmaceutical Society of Japan
Subject
Health, Toxicology and Mutagenesis,Toxicology
Link
http://www.jstage.jst.go.jp/article/jhs/57/1/57_1_22/_pdf
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5. Studies on the Metabolism of Troglitazone to Reactive Intermediates in Vitro and in Vivo. Evidence for Novel Biotransformation Pathways Involving Quinone Methide Formation and Thiazolidinedione Ring Scission
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