Statistical Issues of QT Prolongation Assessment Based on Linear Concentration Modeling-Reference-Cited by-同舟云学术

Statistical Issues of QT Prolongation Assessment Based on Linear Concentration Modeling

Published:2008-05-08 Issue:3 Volume:18 Page:564-584
ISSN:1054-3406
Container-title:Journal of Biopharmaceutical Statistics
language:en
Short-container-title:Journal of Biopharmaceutical Statistics

Author:

Tsong Yi¹,Shen Meiyu¹,Zhong Jinglin¹,Zhang Joanne¹

Affiliation:

1. a Division of Biometrics VI, Office of Biostatistics/Office of Translational Science , Center for Drug Evaluation and Research, U.S. Food and Drug Administration , Silver Spring, Maryland, USA

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Pharmacology,Statistics and Probability

Link

https://www.tandfonline.com/doi/pdf/10.1080/10543400801995502

Reference11 articles.

1. Stereoselective halofantrine disposition and effect:concentration-related QTc prolongation

2. Loratadine and terfenadine interaction with nefazodone: Both antihistamines are associated with QTc prolongation

3. Bioequivalence trials, intersection-union tests and equivalence confidence sets

4. QT prolongation and proarrhythmia by moxifloxacin: concordance of preclinical models in relation to clinical outcome

5. Concentration-QT Relationships Play a Key Role in the Evaluation of Proarrhythmic Risk During Regulatory Review

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