Population pharmacokinetic/pharmacodynamic modeling of delayed effect of escitalopram-induced QT prolongation

Author:

Kim YunORCID,Kim Anhye,Chung Jae-Yong

Publisher

Elsevier BV

Subject

Psychiatry and Mental health,Clinical Psychology

Reference41 articles.

1. U.S. FDA., 2012. FDA drug safety communication: revised recommendations for Celexa (citalopram hydrobromide) related to a potential risk of abnormal heart rhythms with high doses.

2. Medicines and Healthcare products Regulatory Agency., 2014. Citalopram and escitalopram: QT interval prolongation-New maximum daily dose restrictions (including in elderly patients), contraindications, and warnings. Published 11 December 2014. Medicines and Healthcare products Regulatory Agency.

3. Health Canada., 2012. Antidepressant cipralex (escitalopram): updated information regarding dose-related heart risk.

4. Allergan USA, Inc. Lexapro® (escitalopram oxalate) [Prescribing Information]. 2017. Available online: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021323s047lbl.pdf (accessed on December 2019).

5. A population pharmacokinetic model for R- and S-citalopram and desmethylcitalopram in Alzheimer’s disease patients with agitation;Akil;J. Pharmacokinet. Pharmacodyn.,2016

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