Induced degradation of protein kinases by bifunctional small molecules: a next-generation strategy
Author:
Affiliation:
1. Department of Biomedical Sciences, Texas A&M University College of Dentistry, Dallas, TX, USA
Funder
International Fibrodysplasia Ossificans Progressiva Association
Publisher
Informa UK Limited
Subject
Drug Discovery
Link
https://www.tandfonline.com/doi/pdf/10.1080/17460441.2019.1660641
Reference122 articles.
1. Try Me: Promiscuous Inhibitors Still Allow for Selective Targeted Protein Degradation
2. Targeted Protein Degradation: from Chemical Biology to Drug Discovery
3. Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS
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5. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs
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