Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Author:
Funder
NIH
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry
Reference118 articles.
1. What is the right dose? The elusive optimal biologic dose in phase I clinical trials;Adjei;J. Clin. Oncol.,2006
2. Targeted degradation of BET proteins in triple-negative breast cancer;Bai;Cancer Res.,2017
3. Use of PROTACS as molecular probes of angiogenesis;Bargagna-Mohan;Bioorg. Med. Chem. Lett.,2005
4. New insights into ubiquitin E3 ligase mechanism;Berndsen;Nat. Struct. Mol. Biol.,2014
5. E3 ubiquitin ligases as drug targets and prognostic biomarkers in melanoma;Bielskiene;Medicina (Kaunas),2015
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