What Is the Right Dose? The Elusive Optimal Biologic Dose in Phase I Clinical Trials-Reference-Cited by-同舟云学术

What Is the Right Dose? The Elusive Optimal Biologic Dose in Phase I Clinical Trials

Published:2006-09-01 Issue:25 Volume:24 Page:4054-4055
ISSN:0732-183X
Container-title:Journal of Clinical Oncology
language:en
Short-container-title:JCO

Author:

Adjei Alex A.¹

Affiliation:

1. Department of Oncology, Mayo Clinic, Rochester, MN

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

Link

http://ascopubs.org/doi/pdfdirect/10.1200/JCO.2006.07.4658

Reference7 articles.

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2. Skipper HE, Schabel FM, Mellett LB, et al: Implications of biochemical, cytokinetic, pharmacologic, and toxicologic relationships in the design of optimal therapeutic schedules. Cancer Chemother Rep 54:431,1970-450,

3. Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangiogenic activity

4. Phase I Dose Escalation and Pharmacokinetic Study of Enzastaurin, an Oral Protein Kinase C Beta Inhibitor, in Patients With Advanced Cancer

5. Phase I and Pharmacodynamic Study of the Oral MEK Inhibitor CI-1040 in Patients With Advanced Malignancies

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