Electrostatic interaction of tumor-targeting adenoviruses with aminoclay acquires enhanced infectivity to tumor cells inside the bladder and has better cytotoxic activity

Author:

Kim Soo-Yeon1,Kwon Whi-An2,Shin Seung-Pil1,Seo Ho Kyung3,Lim Soo-Jeong4,Jung Yuh-Seog1,Han Hyo-Kyung5,Jeong Kyung-Chae6,Lee Sang-Jin1

Affiliation:

1. Immunotherapeutics Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi-do, Korea;

2. School of Medicine, Institute of Wonkwang Medical Science, Wonkwang University, Wonkwang Univ. Sanbon Hospital, Sanbon, Korea;

3. Biomarker Branch, Research Institute, National Cancer Center, Center for Prostate Cancer, Hospital, Goyang, Gyeonggi-do, Korea;

4. Department of Bioscience and Bioengineering, Sejong University, Seoul, Korea;

5. College of Pharmacy, Dongguk University-Seoul, Goyang, Gyeonggi-do, Korea;

6. Translational Research Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi-do, Korea

Funder

National Research Foundation of Korea

Publisher

Informa UK Limited

Subject

Pharmaceutical Science,General Medicine

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