Intravesical Ad-IFNα Causes Marked Regression of Human Bladder Cancer Growing Orthotopically in Nude Mice and Overcomes Resistance to IFN-α Protein

Author:

Benedict William F.,Tao Ziming,Kim Chang-Soo,Zhang Xinqiao,Zhou Jain-Hua,Adam Liana,McConkey David J.,Papageorgiou Angela,Munsell Mark,Philopena Jennifer,Engler Heidrun,Demers William,Maneval Daniel C.,Dinney Colin P.N.,Connor Robert J.

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference19 articles.

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2. Current use and questions concerning intravesical bladder. Cancer Group for Superficial Bladder Cancer;Dalbagni;Urol. Clin. North Am,2002

3. Superficial bladder cancer: the role of interferon-alpha;Belldegrun;J. Urol,1998

4. Salvage intravesical therapy with interferon-alpha 2b plus low dose bacillus Calmette–Guerin is effective in patients with superficial bladder cancer in whom bacillus Calmette–Guerin alone previously failed;O'Donnell;J. Urol,2001

5. Inhibition of tumorigenicity and metastasis of human bladder cancer growing in athymic mice by interferon-beta gene therapy results partially from various antiangiogenic effects including endothelial cell apoptosis;Izawa;Clin. Cancer Res,2002

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