PIM Kinases in AML
Author:
Publisher
Springer New York
Link
http://link.springer.com/content/pdf/10.1007/978-1-4939-1393-0_9
Reference145 articles.
1. Adam M, Pogacic V et al (2006) Targeting PIM kinases impairs survival of hematopoietic cells transformed by kinase inhibitor-sensitive and kinase inhibitor-resistant forms of Fms-like tyrosine kinase 3 and BCR/ABL. Cancer Res 66:3828–3835
2. Agrawal S, Koschmieder S et al (2008) Pim2 complements Flt3 wild-type receptor in hematopoietic progenitor cell transformation. Leukemia 22:78–86
3. Aho TL, Sandholm J et al (2004) Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site. FEBS Lett 571:43–9
4. Aho TL, Sandholm J et al (2006) Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity. BMC Cell Biol 7:21
5. Akue-Gedu R, Rossignol E et al (2009) Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors. J Med Chem 52:6369–6381
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1. Protein profiling identifies mTOR pathway modulation and cytostatic effects of Pim kinase inhibitor, AZD1208, in acute myeloid leukemia;Leukemia & Lymphoma;2016-04-07
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