Protein profiling identifies mTOR pathway modulation and cytostatic effects of Pim kinase inhibitor, AZD1208, in acute myeloid leukemia
Author:
Funder
AstraZeneca
Publisher
Informa UK Limited
Subject
Cancer Research,Oncology,Hematology
Link
http://www.tandfonline.com/doi/pdf/10.3109/10428194.2016.1166489
Reference47 articles.
1. For better or for worse: the role of Pim oncogenes in tumorigenesis
2. PIM Kinases in AML
3. Genetic Modeling of PIM Proteins in Cancer: Proviral Tagging and Cooperation with Oncogenes, Tumor Suppressor Genes, and Carcinogens
4. The PIM family of oncoproteins: Small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets
5. Pim-1 Kinase Phosphorylates and Stabilizes 130 kDa FLT3 and Promotes Aberrant STAT5 Signaling in Acute Myeloid Leukemia with FLT3 Internal Tandem Duplication
Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A review on structure-function mechanism and signaling pathway of serine/threonine protein PIM kinases as a therapeutic target;International Journal of Biological Macromolecules;2024-06
2. Targeting Pim kinases in hematological cancers: molecular and clinical review;Molecular Cancer;2023-01-25
3. Targeting PIM2 by JP11646 results in significant antitumor effects in solid tumors;International Journal of Oncology;2022-08-03
4. Toxic effects of AZD1208 on mouse oocytes and its possible mechanisms;Journal of Cellular Physiology;2022-07-19
5. Reverse phase protein arrays in acute leukemia: investigative and methodological challenges;Expert Review of Proteomics;2021-12-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3