Pim-1 Kinase Phosphorylates and Stabilizes 130 kDa FLT3 and Promotes Aberrant STAT5 Signaling in Acute Myeloid Leukemia with FLT3 Internal Tandem Duplication-Reference-Cited by-同舟云学术

Pim-1 Kinase Phosphorylates and Stabilizes 130 kDa FLT3 and Promotes Aberrant STAT5 Signaling in Acute Myeloid Leukemia with FLT3 Internal Tandem Duplication

Published:2013-09-05 Issue:9 Volume:8 Page:e74653
ISSN:1932-6203
Container-title:PLoS ONE
language:en
Short-container-title:PLoS ONE

Author:

Natarajan Karthika,Xie Yingqiu,Burcu Mehmet,Linn Douglas E.,Qiu Yun,Baer Maria R.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference48 articles.

1. The roles of FLT3 in hematopoiesis and leukemia;DG Gilliland;Blood,2002

2. Structural and functional alterations of FLT3 in acute myeloid leukemia;S Meshinchi;Clin Cancer Res,2009

3. FLT3 inhibitors: a story of the old and the new;A Fathi;Curr Opin Hematol,2011

4. Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse;M Levis;Blood,2011

5. Phase IIB trial of oral Midostaurin (PKC412), the FMS-like tyrosine kinase 3 receptor (FLT3) and multi-targeted kinase inhibitor, in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome with either wild-type or mutated FLT3;T Fischer;J Clin Oncol,2010

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