Effect of oxidative polymorphism (debrisoquine/sparteine type) on hepatic first-pass metabolism of bufuralol
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/BF00543330.pdf
Reference20 articles.
1. Dayer P, Balant L, Courvoisier F, Kupfer A, Kubli A, Gorgia A, Fabre J (1982) The genetic control of bufuralol metabolism in man. Eur J Drug Metab Pharmacokinet 7: 73?77
2. Dayer P, Kubli A, Kupfer A, Courvoisier F, Balant L, Fabre J (1982) Defective hydroxylation of bufuralol associated with side-effects of the drug in poor metabolizers. Br J Clin Pharmacol 13: 750?752
3. Dayer P, Balant L, Kupfer A, Courvoisier F, Fabre J (1983) Contribution of the genetic status of oxidative metabolism to variability in the plasma concentrations of beta-adrenoceptor blocking agents. Eur J Clin Pharmacol 24: 797?799
4. Lennard MS, Silas JH, Freestone F, Trevethick J (1982) Defective metabolism of metoprolol in poor hydroxylators of debrisoquine. Br J Clin Pharmacol 14: 301?303
5. Lennard MS, Silas JH, Freestone F, Ramsay L, Tucker GT, Woods H (1982) Oxidation phenotype ? A major determinant of metoprolol metabolism and response. N Engl J Med 307: 1558?1560
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