Defective metabolism of metoprolol in poor hydroxylators of debrisoquine.

Author:

Lennard MS,Silas JH,Freestone S,Trevethick J

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference21 articles.

1. High plasma concentrations of, β-receptor blocking drugs and deficient debrisoquine hydroxylation.;ALVAN;Lancet,1982

2. Nor-triptyline and antipyrine clearance in relation to debrisoquine hydroxylation in man.;BERTILSSON;Life Sci.,1980

3. Metabolism of metoprolol-(3H) in man, the dog and the rat.;BORG;Acta pharmac. tox.,1975

4. Human acetylation polymorphism.;EVANS;J. Lab. clin. Med.,1964

5. A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.;EVANS;J. med. Genet.,1980

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