Using High-Throughput Animal or Cell-Based Models to Functionally Characterize GWAS Signals-Reference-Cited by-同舟云学术

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Using High-Throughput Animal or Cell-Based Models to Functionally Characterize GWAS Signals

Published:2018-05-29 Issue:3 Volume:6 Page:107-115
ISSN:2167-4876
Container-title:Current Genetic Medicine Reports
language:en
Short-container-title:Curr Genet Med Rep

Author:

Dourlen Pierre,Chapuis Julien,Lambert Jean-Charles

Funder

Association France Alzheimer

Alzheimer's Association

Institute Pasteur de Lille

Nord-Pas de Calais Regional Council

French National Foundation on Alzheimer's disease and related disorders

Lille Metropole Communaute Urbaine Council

LABEX DISTALZ

Publisher

Springer Science and Business Media LLC

Subject

General Medicine

Link

http://link.springer.com/article/10.1007/s40142-018-0141-1/fulltext.html

Reference64 articles.

1. Ulirsch JC, Nandakumar SK, Wang L, Giani FC, Zhang X, Rogov P, et al. Systematic functional dissection of common genetic variation affecting red blood cell traits. Cell. 2016;165:1530–45.

2. Jones L, Lambert JC, Wang LS, Choi SH, Harold D, Vedernikov A, et al. Convergent genetic and expression data implicate immunity in Alzheimer’s disease. Alzheimers Dement. 2015;11:658–71.

3. Huang K-L, Marcora E, Pimenova AA, Di Narzo AF, Kapoor M, Jin SC, et al. A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer’s disease. Nat Neurosci. 2017;20:1052–61.

4. Sin O, Michels H, Nollen E a a. Genetic screens in Caenorhabditis elegans models for neurodegenerative diseases. Biochim Biophys Acta Mol Basis Dis Elsevier BV. 2014;1842:1951–9.

5. Mukherjee S, Russell JC, Carr DT, Burgess JD, Allen M, Serie DJ, et al. Systems biology approach to late-onset Alzheimer’s disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments. Alzheimers Dement. 2017;13:1133–42.

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