Systems biology approach to late‐onset Alzheimer's disease genome‐wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments-Reference-Cited by-同舟云学术

Systems biology approach to late‐onset Alzheimer's disease genome‐wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments

Published:2017-02-24 Issue:10 Volume:13 Page:1133-1142
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Mukherjee Shubhabrata¹,Russell Joshua C.²,Carr Daniel T.²,Burgess Jeremy D.³,Allen Mariet³,Serie Daniel J.⁴,Boehme Kevin L.⁵⁶,Kauwe John S.K.⁵⁶,Naj Adam C.⁷,Fardo David W.⁸,Dickson Dennis W.³,Montine Thomas J.²,Ertekin‐Taner Nilufer³⁹,Kaeberlein Matt R.²,Crane Paul K.¹

Affiliation:

1. Department of Medicine University of Washington Seattle Washington USA

2. Department of Pathology University of Washington Seattle Washington USA

3. Department of Neuroscience Mayo Clinic Florida Jacksonville Florida USA

4. Department of Health Sciences Research Mayo Clinic Florida Jacksonville Florida USA

5. Department of Biology Brigham Young University Provo Utah USA

6. Department of Neuroscience Brigham Young University Provo Utah USA

7. Department of Biostatistics and Epidemiology, Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA

8. Department of Biostatistics University of Kentucky Lexington Kentucky USA

9. Department of Neurology Mayo Clinic Florida Jacksonville Florida USA

Funder

Labex

Institut National de la Santé et de la Recherche Médicale

Alzheimer’s Research UK

National Institute on Aging

National Heart, Lung, and Blood Institute

Alzheimer's Association

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Clinical Neurology,Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1016/j.jalz.2017.01.016

Reference46 articles.

1. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

2. Gene and pathway-based second-wave analysis of genome-wide association studies

3. Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

4. Convergent genetic and expression data implicate immunity in Alzheimer's disease

5. MicroRNA regulation of human protein–protein interaction network

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