FSIP1 enhances the therapeutic sensitivity to CDK4/6 inhibitors in triple-negative breast cancer patients by activating the Nanog pathway-Reference-Cited by-同舟云学术

FSIP1 enhances the therapeutic sensitivity to CDK4/6 inhibitors in triple-negative breast cancer patients by activating the Nanog pathway

Published:2023-07-14 Issue: Volume: Page:
ISSN:1674-7305
Container-title:Science China Life Sciences
language:en
Short-container-title:Sci. China Life Sci.

Author:

Chen Guanglei,Sun Lisha,Gu Xi,Ai Liping,Yang Jie,Zhang Zhan,Hou Pengjie,Wang Yining,Ou Xunyan,Jiang Xiaofan,Qiao Xinbo,Ma Qingtian,Niu Nan,Xue Jinqi,Zhang Hao,Yang Yongliang,Liu Caigang

Publisher

Springer Science and Business Media LLC

Subject

General Agricultural and Biological Sciences,General Environmental Science,General Biochemistry, Genetics and Molecular Biology

Link

https://link.springer.com/content/pdf/10.1007/s11427-023-2343-y.pdf

Reference35 articles.

1. Álvarez-Fernández, M., and Malumbres, M. (2020). Mechanisms of sensitivity and resistance to CDK4/6 inhibition. Cancer Cell 37, 514–529.

2. Bianchini, G., Balko, J.M., Mayer, I.A., Sanders, M.E., and Gianni, L. (2016). Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease. Nat Rev Clin Oncol 13, 674–690.

3. Cai, Z., Wang, J., Li, Y., Shi, Q., Jin, L., Li, S., Zhu, M., Wang, Q., Wong, L.L., Yang, W., et al. (2023). Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in breast cancer that can be reversed by PI3K/mTOR inhibitors. Sci China Life Sci 66, 94–109.

4. Cappell, K.M., Sinnott, R., Taus, P., Maxfield, K., Scarbrough, M., and Whitehurst, A.W. (2012). Multiple cancer testis antigens function to support tumor cell mitotic fidelity. Mol Cell Biol 32, 4131–4140.

5. Carey, L.A. (2021). Finding the positive in triple-negative breast cancer. Nat Cancer 2, 476–478.

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