Low Reynolds Number Viscous Flow in an Alveolated Duct-Reference-Cited by-同舟云学术

Low Reynolds Number Viscous Flow in an Alveolated Duct

Published:2004-08-01 Issue:4 Volume:126 Page:420-429
ISSN:0148-0731
Container-title:Journal of Biomechanical Engineering
language:en
Short-container-title:

Author:

Karl Alexander¹,Henry Frank S.²,Tsuda Akira³

Affiliation:

1. Institut fu¨r Thermodynamik der Luft- und Raumfahrt, University of Stuttgart, Stuttgart, 70550, Germany

2. School of Engineering and Mathematical Sciences, City University, London, U.K., EC1 V0HB

3. Physiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115

Abstract

Flow visualization studies and supplementary numerical simulations are carried out on slow flow through a model alveolated duct. The results reveal that the type of flow that develops in the alveoli, or cavities, is controlled by the ratio of the depth to the width of the cavity and by the ratio of cavity volume to duct volume. While weak, the slowly rotating flow in the cavity is thought to be important to the convective transport of heat and mass transfer to, or from, the walls of the cavity. The relevance of these finding to particle transport and deposition deep in the lung is discussed.

Publisher

ASME International

Subject

Physiology (medical),Biomedical Engineering

Link

http://asmedigitalcollection.asme.org/biomechanical/article-pdf/126/4/420/5503366/420_1.pdf

Reference23 articles.

1. Frederspiel, W. J., and Fredberg, J. J., 1988, “Axial dispersion in alveolar ducts and respiratory bronchioles,” J. Appl. Physiol., 64(6), pp. 2414–2621.

2. Tsuda, A., Federspiel, W. J., Grant, Jr., P. A., and Fredberg, J. J., 1991, “Axial dispersion of inert species in alveolated channels,” Chem. Eng. Sci., 46, pp. 1419–1426.

3. Tsuda, A., Butler, J. P., and Fredberg, J. J., 1994, “Effects of alveolated duct structure on aerosol kinetics. I. Diffusional deposition in the absence of gravity,” J. Appl. Physiol., 76(6), pp. 2497–2509.

4. Tsuda, A., Butler, J. P., and Fredberg, J. J., 1994, “Effects of alveolated duct structure on aerosol kinetics. II. Gravitational sedimentation and inertial impaction,” J. Appl. Physiol., 76(6), pp. 2510–2516.

5. Darquenne, C., and Paiva, M., 1996, “Two- and three-dimensional simulations of aerosol transport and deposition in alveolar zone of human lung,” J. Appl. Physiol., 80, pp. 2889–2898.

Cited by 51 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Exploring the role of electrostatic deposition on inhaled aerosols in alveolated microchannels;Scientific Reports;2023-12-27

2. Fluid dynamics in intracranial aneurysms treated with flow-diverting stents: effect of multiple geometrical parameters;Journal of Fluid Mechanics;2023-10-23

3. Surface tension effects on flow dynamics and alveolar mechanics in the acinar region of human lung;Heliyon;2022-10

4. Analysis and characterization of diffusive flows and movement of the human acinar region: An experimentally validated CFD model;Computers & Fluids;2022-06

5. Surface Tension Effects on Flow Dynamics and Alveolar Mechanics in the Acinar Region of Human Lung;SSRN Electronic Journal;2022