High Levels of Serum Uric Acid Predict Severity of Coronary Artery Disease in Patients with Acute Coronary Syndrome-Reference-Cited by-同舟云学术

High Levels of Serum Uric Acid Predict Severity of Coronary Artery Disease in Patients with Acute Coronary Syndrome

Published:2011-11-17 Issue:6 Volume:63 Page:448-452
ISSN:0003-3197
Container-title:Angiology
language:en
Short-container-title:Angiology

Author:

Duran Mustafa¹,Kalay Nihat²,Akpek Mahmut²,Orscelik Ozcan²,Elcik Deniz²,Ocak Ayse³,Inanc Mehmet Tugrul²,Kasapkara H. Ahmet⁴,Oguzhan Abdurrahman²,Eryol Namik K.²,Ergin Ali²,Kaya Mehmet Gungor²

Affiliation:

1. Department of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey

2. Department of Cardiology, Erciyes University, Kayseri, Turkey

3. Department of Internal Medicine, Erciyes University, Kayseri, Turkey

4. Ataturk Training and Research Hospital, Cardiology, Ankara, Turkey

Abstract

We aimed to elucidate the relation between serum uric acid (SUA) level and severity of coronary artery disease (CAD) in nondiabetic, nonhypertensive patients (n = 246) with acute coronary syndrome (ACS). Severity of CAD was assessed by the Gensini score. One, 2, and 3 or more diseased vessels were identified in 87 (35.4%), 55 (22.4%), and 104 (42.2%) patients, respectively. Patients with hyperuricemia had higher Gensini score, high number of diseased vessels, critical lesions, and total occlusion. Serum uric acid level was significantly associated with number of diseased vessels. Serum uric acid was an independent risk factor for multivessel disease by univariate analysis. High levels of SUA associated with the severity of CAD in nondiabetic, nonhypertensive patients with ACS.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/0003319711426868

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