Attention Skills in Children With Neurofibromatosis Type 1

Author:

Isenberg Jill C.1,Templer Alexandra1,Gao Feng2,Titus Jeffrey B.34,Gutmann David H.1

Affiliation:

1. Department of Neurology, Washington University School of Medicine, St Louis, MO, USA

2. Division of Biostatistics, Washington University School of Medicine, St Louis, MO, USA

3. Pediatric Neuropsychology, Dell Children’s Medical Center, Austin, TX, USA

4. Department of Psychology, University of Texas at Austin, Austin, TX, USA

Abstract

Children with neurofibromatosis type 1 are at increased risk for the development of attention problems relative to their unaffected peers. Previous studies have reported deficits in sustained auditory attention, but other aspects of attention, including sustained visual attention, divided attention, response inhibition, and selective attention, have not been consistently documented. In the present study, we specifically investigated attention skills in children with neurofibromatosis type 1 using measures of visual and sustained auditory attention, divided attention, selective attention, and response inhibition. Consistent with previous reports, we confirmed the presence of deficits in sustained visual and auditory attention in children with neurofibromatosis type 1 but also identified deficits in divided attention and response inhibition. Based on the high frequency and wide spectrum of attention system impairments in this at-risk population, we advocate screening children with neurofibromatosis type 1 for attention problems and providing appropriate interventions that address all aspects of their executive functioning.

Publisher

SAGE Publications

Subject

Clinical Neurology,Pediatrics, Perinatology, and Child Health

Reference24 articles.

1. Epidemiology of neurofibromatosis type 1

2. National Institutes of Health Consensus Development Conference Statement: neurofibromatosis. Bethesda, Md., USA; July 13–15, 1987. Neurofibromatosis 1988;1(3):172–178. (accessed 2011 September 26).

3. Review Article : Cognitive Deficits in Neurofibromatosis 1

4. The nature and frequency of cognitive deficits in children with neurofibromatosis type 1

5. Neurofibromatosis type 1: New insights into neurocognitive issues

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