Synthesis and Structure Activity Relationships of a Series of Penicillin-Derived Pseudosymmetric Inhibitors of HIV-1 Proteinase
Author:
Affiliation:
1. Departments of Medicinal Chemistry II, Glaxo Group Research Limited, Greenford, Middlesex, UB6 0HE, UK
2. Departments of Virology, Glaxo Group Research Limited, Greenford, Middlesex, UB6 0HE, UK
Abstract
Publisher
SAGE Publications
Link
http://journals.sagepub.com/doi/pdf/10.1177/095632029400500311
Reference14 articles.
1. Carbovir: the (—) enantiomer is a potent and selective antiviral agent against human immunodeficiency virus in vitro
2. The HIV-1 Protease as a Therapeutic Target for AIDS
3. Design, Activity, and 2.8 Å Crystal Structure of a C 2 Symmetric Inhibitor Complexed to HIV-1 Protease
4. Discovery and Analysis of a Series of C2-Symmetric HIV-1 Proteinase Inhibitors Derived from Penicillin
5. Novel dimeric penicillin derived inhibitors of HIV-1 proteinase: interaction with the catalytic aspartates
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Approaches to the Design of Effective HIV-1 Protease Inhibitors;Current Medicinal Chemistry;2000-04-01
2. Chapter 15. Antiviral Agents;Annual Reports in Medicinal Chemistry;1995
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