Carbovir: the (—) enantiomer is a potent and selective antiviral agent against human immunodeficiency virus in vitro

Author:

Coates Jonathan A.V.,Inggall Helen J.,Pearson Bridget A.,Penn Charles R.,Storer Richard,Williamson Christopher,Cameron Janet M.

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference21 articles.

1. Both 2′,3′-dideoxythymidine and its 2′,3′-unsaturated derivative (2′,3′-dideoxythymidine) are potent and selective inhibitors of Human Immunodeficiency Virus replication in vitro;Baba;Biochem. Biophys. Res. Commun.,1987

2. Potent and selective anti-HTL VIII/LAV activity of 2′,3′-dideoxycytidinene, the 2′,3′-unsaturated derivative of 2′,3′-dideoxycytidine;Balzarini;Biochem. Biophys. Res. Commun.,1986

3. Carbocyclic 5-iodo-2′-deoxyuridine (C-IDU) and carbocyclic (E)-5-(2-bromovinyl)-2′-deoxyuridine (C-BVdU) as unique examples of chiral molecules where the two enantiomeric forms are biologically active: interaction of the (+) and (−) enantiomers of C-IDU and C-BVdU with the thymidine kinase of herpes simplex virus type 1;Balzarini;Mol. Pharmacol.,1990

4. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS);Barré-Sinoussi;Science,1983

5. Studies on the biochemical basis for the antiviral activities of some nucleoside analogues;Bennett;Ann. N.Y. Acad. Sci.,1975

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