Elimination of Microbubbles from the Extracorporeal Circuit: Dynamic Bubble Trap versus Arterial Filter

Abstract

Background Open heart surgery is associated with important risk of cerebral and peripheral organ dysfunction, attributed in part to microbubbles generated in or not eliminated from the ECC. For elimination of microbubbles, a dynamic bubble trap (DBT(tm)) was developed for the arterial line of ECCs. Methods Bubble eliminating properties of an arterial filter were evaluated in four CABG patients and compared to the performance of the DBT in four patients. One patient received both devices. Results Elimination of bubbles between 40–120μm was significantly higher with the DBT (88% vs. 57% with arterial filter, p=0.034). Reduction of bubbles below 40μm was equivalent in both groups. The combination of both devices was most effective (94% for bubbles >40μm). Conclusion Arterial filter and DBT are equally effective in elimination of smaller gas bubbles. However, bigger bubbles possibly causing cerebral and peripheral organ damage are eliminated to a greater degree by the DBT.