Conditional Deletion of PTEN in Peripheral T Cells Augments TCR-Mediated Activation but Does Not Abrogate CD28 Dependency or Prevent Anergy Induction-Reference-Cited by-同舟云学术

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Conditional Deletion of PTEN in Peripheral T Cells Augments TCR-Mediated Activation but Does Not Abrogate CD28 Dependency or Prevent Anergy Induction

Published:2013-07-12 Issue:4 Volume:191 Page:1677-1685
ISSN:0022-1767
Container-title:The Journal of Immunology
language:en
Short-container-title:J.I.

Author:

Locke Frederick L.,Zha Yuan-yuan,Zheng Yan,Driessens Gregory,Gajewski Thomas F.

Publisher

The American Association of Immunologists

Subject

Immunology,Immunology and Allergy

Reference45 articles.

1. PTEN: Life as a Tumor Suppressor

2. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

3. Tenets of PTEN Tumor Suppression

4. The phosphatidylinositol phosphatase PTEN is under control of costimulation and regulates proliferation in human T cells

5. Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-γ but not TH2 cytokines

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