Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia-Reference-Cited by-同舟云学术

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

Published:2007-09-16 Issue:10 Volume:13 Page:1203-1210
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Palomero Teresa,Sulis Maria Luisa,Cortina Maria,Real Pedro J,Barnes Kelly,Ciofani Maria,Caparros Esther,Buteau Jean,Brown Kristy,Perkins Sherrie L,Bhagat Govind,Agarwal Archana M,Basso Giuseppe,Castillo Mireia,Nagase Satoru,Cordon-Cardo Carlos,Parsons Ramon,Zúñiga-Pflücker Juan Carlos,Dominguez Maria,Ferrando Adolfo A

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm1636.pdf

Reference49 articles.

1. Grabher, C., von Boehmer, H. & Look, A.T. Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia. Nat. Rev. Cancer 6, 347–359 (2006).

2. Weng, A.P. et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306, 269–271 (2004).

3. Stylianou, S., Clarke, R.B. & Brennan, K. Aberrant activation of Notch signaling in human breast cancer. Cancer Res. 66, 1517–1525 (2006).

4. Purow, B.W. et al. Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation. Cancer Res. 65, 2353–2363 (2005).

5. Pahlman, S., Stockhausen, M.T., Fredlund, E. & Axelson, H. Notch signaling in neuroblastoma. Semin. Cancer Biol. 14, 365–373 (2004).

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