A novel <i>TCF3::PIK3R1</i> fusion linked to decreased <scp>PI3K</scp>‐<scp>AKT</scp> signalling activity in paediatric B‐acute lymphoblastic leukaemia-Reference-Cited by-同舟云学术

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A novel TCF3::PIK3R1 fusion linked to decreased PI3K‐AKT signalling activity in paediatric B‐acute lymphoblastic leukaemia

Published:2024-06-14 Issue:2 Volume:205 Page:738-741
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:Br J Haematol

Author:

Grady Emma¹,Biswas Sharmila¹,Dias Tânia¹,McCarthy Peter¹²,Tudose Cosmin¹³,Betts David⁴,Malone Andrea²,Bond Jonathan¹²^ORCID

Affiliation:

1. Systems Biology Ireland, School of Medicine University College Dublin Dublin Ireland

2. National Children's Cancer Service Children's Health Ireland at Crumlin Dublin Ireland

3. SFI Centre for Research Training in Genomics Data Science Dublin Ireland

4. Department of Clinical Genetics Children's Health Ireland at Crumlin Dublin Ireland

Funder

Science Foundation Ireland

Horizon 2020 Framework Programme

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.19587

Reference14 articles.

1. Cryptic TCF3 fusions in childhood leukemia: Detection by RNA sequencing

2. Clinical and Molecular Characteristics of TCF3-Hlf Gene Fusion-Positive B-Cell Precursor Acute Lymphoblastic Leukemia: A Series of 24 Cases from a Large Cohort of Leukemia Patients

3. Prognostic impact of t(1;19)/TCF3–PBX1in childhood acute lymphoblastic leukemia in the context of Berlin–Frankfurt–Münster-based protocols

4. Whole-transcriptome analysis in acute lymphoblastic leukemia: a report from the DFCI ALL Consortium Protocol 16-001

5. Excellent outcome of acute lymphoblastic leukaemia withTCF3-PBX1rearrangement in Hong Kong

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