Nuclear magnetic resonance structure-based drug design
Author:
Affiliation:
1. Laboratory of Physical Chemistry, ETH Zürich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland
Publisher
Future Science Ltd
Subject
Drug Discovery,Pharmacology,Molecular Medicine
Link
http://www.future-science.com/doi/pdf/10.4155/fmc-2018-0160
Reference20 articles.
1. Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser
2. Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis
3. NMR in drug discovery: A practical guide to identification and validation of ligands interacting with biological macromolecules
4. NMR-Based Determination of the 3D Structure of the Ligand–Protein Interaction Site without Protein Resonance Assignment
5. Protein−Ligand NOE Matching: A High-Throughput Method for Binding Pose Evaluation That Does Not Require Protein NMR Resonance Assignments
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2. Protein—ligand structure determination with the NMR molecular replacement tool, NMR2;Journal of Biomolecular NMR;2020-07-03
3. Protein–fragment complex structures derived by NMR molecular replacement;RSC Medicinal Chemistry;2020
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