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NMR Molecular Replacement Provides New Insights into Binding Modes to Bromodomains of BRD4 and TRIM24

  • Published:2022-03-31 Issue:7 Volume:65 Page:5565-5574
  • ISSN:0022-2623
  • Container-title:Journal of Medicinal Chemistry
  • language:en
  • Short-container-title:J. Med. Chem.

Author:

Torres Felix1,Walser Reto2ORCID,Kaderli Janina1,Rossi Emanuele1,Bobby Romel2,Packer Martin J.3,Sarda Sunil2,Walker Graeme4,Hitchin James R.4,Milbradt Alexander G.2,Orts Julien15ORCID

Affiliation:

1. Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, HCI F217, Eidgenossische Technische Hochschule Zurich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland

2. BioPharmaceuticals R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom

3. Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom

4. Drug Discovery Unit, Cancer Research UK Manchester Institute, Alderley Park, Macclesfield SK10 4TG, United Kingdom

5. Department of Pharmaceutical Sciences, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria

Funder

AstraZeneca

Eidgen?ssische Technische Hochschule Z?rich

Universit?t Wien

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A Benchmark Study of Protein–Fragment Complex Structure Calculations with NMR2;International Journal of Molecular Sciences;2023-09-20
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