Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis-Reference-Cited by-同舟云学术

Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis

Published:2017-03-13 Issue:6 Volume:2 Page:
ISSN:2058-5276
Container-title:Nature Microbiology
language:en
Short-container-title:Nat Microbiol

Author:

Wong Wilson,Bai Xiao-Chen,Sleebs Brad E.^ORCID,Triglia Tony,Brown Alan,Thompson Jennifer K.,Jackson Katherine E.,Hanssen Eric^ORCID,Marapana Danushka S.,Fernandez Israel S.,Ralph Stuart A.,Cowman Alan F.,Scheres Sjors H. W.^ORCID,Baum Jake

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Microbiology (medical),Genetics,Applied Microbiology and Biotechnology,Immunology,Microbiology

Link

http://www.nature.com/articles/nmicrobiol201731.pdf

Reference50 articles.

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2. White, N. J. et al. Malaria. Lancet 383, 723–735 (2014).

3. Wells, T. N., Hooft van Huijsduijnen, R. & Van Voorhis, W. C. Malaria medicines: a glass half full? Nat. Rev. Drug Discov. 14, 424–442 (2015).

4. Nevin, R. L. & Byrd, A. M. Neuropsychiatric adverse reactions to mefloquine: a systematic comparison of prescribing and patient safety guidance in the US, UK, Ireland, Australia, New Zealand, and Canada. Neurol. Ther. 5, 69–83 (2016).

5. Lim, P. et al. Decreasing pfmdr1 copy number suggests that Plasmodium falciparum in western Cambodia is regaining in vitro susceptibility to mefloquine. Antimicrob. Agents Chemother. 59, 2934–2937 (2015).

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