Affiliation:
1. Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous, Ananthapuramu, Andhra Pradesh, India.
Abstract
The present article concentrates on the Buccal film. It is a buccoadhesive drug delivery system that enhances the safety, efficacy, and stability of active pharmaceutical ingredients. The buccal film is a novel technology due to its better option to optimize therapeutic efficacy. This drug delivery system is suitable for drugs that pass through high first-pass metabolism and are used for enhancing bioavailability. The buccal film can be formulated as a solvent casting, semi-solid casting, hot-melt extrusion, solid dispersion, or rolling method. Among them, the solvent casting method is mostly adopted. The buccal films are evaluated for mechanical properties viz., Organoleptic assessment, thickness, dryness, tack test, tensile strength, percent elongation, folding endurance, swelling assets, surface pH, contact angle, transparency, uniformity in drug content, disintegration, and in-vitro dissolution tests. The article gave a handful of literature on past work done on buccal films. This article helps with quick references to the earlier attempts so far made on buccal films.
Reference44 articles.
1. Ahad HA, Chinthaginjala H, Priyanka MS, Raghav DR, Gowthami M, Jyothi VN. Datura stramonium Leaves Mucilage Aided Buccoadhesive Films of Aceclofenac using 32 Factorial Design with Design-Expert Software.
2. Kumria R, Nair AB, Goomber G, Gupta S. Buccal films of prednisolone with enhanced bioavailability. Drug delivery. 2016 Feb 12;23(2):471-8.
3. Ahad HA, Ksheerasagare T, Chelluru A, Haranath C, Reddy GS, Krishna JV. Herbal Mucilage attempted as a Super disintegrating agent in Oral Disintegrating Tablets. Research Journal of Pharmacy and Technology. 2020 Nov 1;13(11):5489-92.
4. Al-Dhubiab BE, Nair AB, Kumria R, Attimarad M, Harsha S. Development, and evaluation of buccal films impregnated with selegiline-loaded nanospheres. Drug delivery. 2016 Sep 1;23(7):2154-62.
5. Hindustan AA, Babu UA, Nagesh K, Kiran DS, Madhavi KB. Fabrication of glimepiride Datura stramonium leaves mucilage and poly vinyl pyrrolidone sustained release matrix tablets: in vitro evaluation. Kathmandu university journal of science, engineering, and technology. 2012;8(1):63-72.
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