Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions-Reference-Cited by-同舟云学术

Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions

Published:1997-12 Issue:5 Volume:274 Page:738-747
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Maga Giovanni,Amacker Mario,Ruel Nancy,Hübscher Ulrich,Spadari Silvio

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference37 articles.

1. Analysis of inhibition of retroviral reverse transcriptase;Balzarini;Methods Enzymol.,1996

2. HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase;Balzarini;Virology,1993

3. Concomitant combination therapy for HIV infection preferable over sequential therapy with 3TC and non-nucleoside reverse transcriptase inhibitors;Balzarini;Proc. Natl Acad. Sci. USA,1996

4. Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase;Boyer;J. Virol.,1993

5. Drug resistance of human immunodeficiency virus type 1 reverse transcriptase;Boyer;Antimicrob. Agents Chemother.,1994

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