Effect of α-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3H)-ones-Reference-Cited by-同舟云学术

Effect of α-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3H)-ones

Published:2018-12-07 Issue:2 Volume:62 Page:604-621
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nawrozkij Maxim B.¹,Forgione Mariantonietta²,Yablokov Alexandre S.¹,Lucidi Alessia²,Tomaselli Daniela²,Patsilinakos Alexandros²,Panella Cristina³,Hailu Gebremedhin S.²,Kirillov Ivan A.¹,Badia Roger⁴^ORCID,Riveira-Muñoz Eva⁴^ORCID,Crespan Emmanuele⁵^ORCID,Armijos Rivera Jorge I.⁵,Cirilli Roberto³^ORCID,Ragno Rino²^ORCID,Esté José A.⁴^ORCID,Maga Giovanni⁵^ORCID,Mai Antonello²⁶^ORCID,Rotili Dante²

Affiliation:

1. Volgograd State Technical University, Lenina Avenue 28, 400005 Volgograd, Russia

2. Dipartimento di Chimica e Tecnologie del Farmaco, Università degli Studi di Roma “La Sapienza”, P. le A. Moro 5, 00185 Roma, Italy

3. Centro Nazionale per il Controllo e la Valutazione dei Farmaci, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Roma, Italy

4. IrsiCaixa-AIDS Research Institute, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain

5. Istituto di Genetica Molecolare IGM-CNR, via Abbiategrasso 207, 27100 Pavia, Italy

6. Istituto Pasteur—Fondazione Cenci Bolognetti, Università degli Studi di Roma “La Sapienza”, P. le A. Moro 5, 00185 Roma, Italy

Funder

Ministerio de Econom?a y Competitividad

Russian Foundation for Basic Research

Council for Grants of the President of the Russian Federation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01238

Reference54 articles.

1. HIV-1 NNRTIs: structural diversity, pharmacophore similarity, and impliations for drug design

2. Synthesis, antimicrobial and antiviral activities of isotrimethoprim and some related derivatives

3. 3,4-Dihydro-2-Alkoxy-6-Benzyl-4-Oxopyrimidines (DABOs): A New Class of Specific Inhibitors of Human Immunodeficiency Virus Type 1

4. Synthesis and Antiviral Activity of New 3,4-Dihydro-2-Alkoxy-6-Benzyl-4-Oxopyrimidines (DABOs), Specific Inhibitors of Human Immunodeficiency Virus Type 1

5. Recent Advances in the DABOs Family as Potent HIV-1 non-Nucleoside Reverse Transcriptase Inhibitors

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