HIV-1 NNRTIs: structural diversity, pharmacophore similarity, and impliations for drug design

Author:

Zhan Peng1,Chen Xuwang1,Li Dongyue1,Fang Zengjun1,De Clercq Erik2,Liu Xinyong1

Affiliation:

1. Department of Medicinal Chemistry, School of Pharmaceutical Sciences; Shandong University; Jinan; Shandong; P.R. China

2. Rega Institute for Medical Research, Katholieke Universiteit; Leuven; Leuven; Belgium

Publisher

Wiley

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Reference369 articles.

1. Nonnucleoside inhibitors of HIV-1 reverse transcriptase: From the biology of reverse transcription to molecular design;Tronchet;Curr Top Med Chem,2003

2. The current status of the NNRTI family of antiretrovirals used in the HAART regime against HIV infection;Martins;Curr Med Chem,2008

3. HIV-1 RT nonnucleoside inhibitors and their interaction with RT for antiviral drug development;Zhou;Infect Disord Drug Targets,2006

4. Etravirine for the treatment of HIV infection;Seminari;Expert Rev Anti Infect Ther,2008

5. Emerging resistance profiles of newly approved antiretroviral drugs;Daar;Top HIV Med,2008

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