Plasma Lipid-lowering Action of Ginseng Saponins and Mechanism of the Action

Author:

Yamamoto Masahiro1,Kumagai Akira1,Yamamura Yuichi1

Affiliation:

1. The 2nd Department of Internal Medicine, Chiba University School of Medicine, Chiba, Japan

Abstract

Elevation of plasma levels of cholesterol and triglyceride was reduced by the intramuscular injection ginseng principles fraction 4 (saponin content, ca. ½). The elimination of intraperitoneally injected 4-[14C]-cholesterol from plasma was accelerated by fraction 4 administration. Fecal excretion [14C] bile acids and [14C] sterols after intraperitoneal injection of 4-[14C]-cholesterol was significantly increased by fraction 4 administration.

Publisher

World Scientific Pub Co Pte Lt

Subject

Complementary and alternative medicine,General Medicine

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