The experimental design and data interpretation in “Unexpected mutations after CRISPR–Cas9 editing in vivo” by Schaefer et al. are insufficient to support the conclusions drawn by the authors-Reference-Cited by-同舟云学术

The experimental design and data interpretation in “Unexpected mutations after CRISPR–Cas9 editing in vivo” by Schaefer et al. are insufficient to support the conclusions drawn by the authors

Published:2017-06-21 Issue: Volume: Page:
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Author:

Wilson Christopher J.,Fennell Tim,Bothmer Anne,Maeder Morgan L.,Reyon Deepak,Cotta-Ramusino Cecilia,Fernandez Cecilia A.,Marco Eugenio,Barrera Luis A.,Jayaram Hariharan,Albright Charles F.,Cox Gerald F.,Church George M.,Myer Vic E.

Publisher

Cold Spring Harbor Laboratory

Reference8 articles.

1. Unexpected mutations after CRISPR–Cas9 editing in vivo

2. Off-target mutations are rare in Cas9-modified mice;Nature Methods,2015

3. Whole-Genome Sequencing Analysis Reveals High Specificity of CRISPR/Cas9 and TALEN-Based Genome Editing in Human iPSCs

4. Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing

5. Genetic and epigenetic variation among inbred mouse littermates: identification of inter-individual differentially methylated regions

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