Reduction of Pyrimidine Derivatives by LiAlH4-Reference-Cited by-同舟云学术

Reduction of Pyrimidine Derivatives by LiAlH4

Published:2007-08 Issue:8 Volume:2007 Page:490-493
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Yu-Xiu Liu¹,Ming-Bo Cui¹,Qi-Qi Zhao¹,Qing-Min Wang¹,Ying Liu²,Run-Qiu Huang¹

Affiliation:

1. State Key Laboratory of Elemento-organic Chemistry, Institute of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China

2. State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China

Abstract

The reduction of ethyl 2-methylthio-(or 2-ethoxy)pyrimidine-5-carboxylate by LiAlH4 afforded ethyl 2-methylthio-(or 2-ethoxy)-1,6-dihydropyrimidine-5-carboxylate as the main product. Similarly, the reduction of 2-methylthio-(or 2-methoxy)pyrimidine-5-carboxamide by LiAlH4 gave 2-methylthio-(or 2-methoxy)-1,6-dihydropyrimidine-5-carbonitrile as main product.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823407X240872

Reference12 articles.

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