Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity
Author:
Affiliation:
1. Department of Pharmacology, University of Texas Health, San Antonio, Texas
Funder
National Institutes of Health
Publisher
Oxford University Press (OUP)
Subject
Pharmacology (medical),Psychiatry and Mental health,Pharmacology
Link
http://academic.oup.com/ijnp/article-pdf/21/10/962/25863743/pyy071.pdf
Reference160 articles.
1. A study of the adrenotropic receptors;Ahlquist;Am J Physiol,1948
2. Computationally-predicted CB1 cannabinoid receptor mutants show distinct patterns of salt-bridges that correlate with their level of constitutive activity reflected in G protein coupling levels, thermal stability, and ligand binding;Ahn;Proteins,2013
3. The effect of mutations in the DRY motif on the constitutive activity and structural instability of the histamine H(2) receptor;Alewijnse;Mol Pharmacol,2000
4. G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity;Allen;Proc Natl Acad Sci U S A,1991
5. Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein homer;Ango;Nature,2001
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